02 — THE HOLISTIC WELL-BEING IMPACT STUDY
Collagen is the most abundant protein in the human body, playing a critical role in the structure, integrity, and function of skin, bones, muscles, tendons, and ligaments. Here's a structured overview of what the comprehensive research study on our collagen as one of our main ingredients involves:
These highly specialized collagen peptides used in Reformed’s products have been shown to decrease fat mass, increase lean body mass and to provide more muscle strength in combination with resistance training.
Muscles are essential for physical activity, stability and posture, they enable blood circulation and help during the digestion of food. A loss of muscle mass over the course of life time means a loss of mobility, which is followed by a loss of independence and a loss of quality of life. In summary, the studies confirm that the intake of Reformed’s collagen results in improvement of mobility in healthy individuals.
Recent investigations revealed our collagen significantly stimulates the mTOR pathway. Availability and activity of this key protein are essential for the protein metabolism. The protein metabolism ensures the balance between protein synthesis and protein degradation. More synthesis than breakdown indicates an anabolic state that builds lean tissues, higher breakdown than synthesis indicates a catabolic state that decreases lean tissues.
Moreover, our collagen has also proven to influence the fat metabolism. A sufficient energy supply is mandatory for the proliferation of muscle cells and the synthesis of new muscle tissue. The AMPK enzyme is responsible for the energy transfer in the muscle cells. The stimulation of AMPK leads to an increase in fatty acid metabolism, which provides more energy for the cells and results in a reduction of fat mass. Due to its specific amino acid composition and its excellent bioavailability, our highly specialized collagen peptides stimulate fat and muscle metabolisms, finally leading to an improved body composition. Studies confirm the efficacy of our Collagen
Numerous studies employing a randomized, placebo-controlled, double-blind design have shown the benefits and effectiveness of consuming 15g of Reformed’s collagen daily alongside resistance training.
Recent research articles 2 and 3 investigated the impact collagen supplementation after exercise on lean body mass, fat mass, and muscle strength when combined with resistance exercises. The studies involved 114 healthy, previously inactive men between the ages of 35 and 60. The main objective was to evaluate the difference between taking 15g of Reformed’s Collagen and a placebo in terms of body composition. Dual-energy X-ray absorptiometry (DXA) scans were used to measure changes in body composition. Recognized as the "Gold Standard" for determining body composition, DXA scans provide accurate assessments of bone mass, lean body mass, and fat mass through comprehensive body scans.
In addition, muscle strength, waist circumference and various blood parameters were determined. The results of the primary endpoint of the study revealed a statistically significant (p<0.05) increase in lean body mass after the mentioned supplementation compared to placebo.